Investigating Nutritional Support Strategies for the Effective Management of Dry Age-Related Macular Degeneration
As experienced optometrists, we regularly receive questions from patients seeking effective methods to protect and enhance their vision, especially when confronted with age-related issues such as macular degeneration. The role of nutrition and supplementation in maintaining optimal eye health is crucial, and an expanding body of clinical research highlights their significant impact on managing dry age-related macular degeneration (AMD).
In this detailed comparison, we will evaluate two well-known products available in the Australian market: Macutec Once Daily and Blackmores Macu-Vision Plus.

Comprehensive Overview of Macular Degeneration and Its Implications
Macular degeneration is a progressive condition that severely affects the macula, the central part of the retina responsible for delivering sharp, high-resolution vision. This disorder ranks among the leading causes of substantial vision loss in Australia, impacting thousands of individuals annually.
There are two predominant types of macular degeneration:
- Dry Macular Degeneration
This form is the more common variant, accounting for approximately 90% of all cases. It involves a gradual thinning of the macular tissue, leading to a slow yet persistent decline in central vision over time. - Wet Macular Degeneration
This variant, though less frequent, is considerably more severe. It arises when abnormal blood vessels develop and leak fluid or blood beneath the macula, often resulting in sudden and irreversible vision loss without prompt medical attention.
What Are the Risks of Not Treating Macular Degeneration Effectively?
- Dry AMD may evolve gradually, but if neglected, it can culminate in significant vision loss over an extended period.
- Wet AMD requires immediate medical intervention to prevent irreversible damage to central vision.
What Are the Most Effective Treatment Options for Macular Degeneration?
- Wet AMD is often treated through injections designed to halt the formation of leaky blood vessels.
- Dry AMD management typically involves a combination of lifestyle changes and nutritional supplements that adhere to the scientifically validated AREDS2 formula.
Why Is Adhering to the AREDS2 Formula Crucial for Treatment?
The Age-Related Eye Disease Studies (AREDS and AREDS2) have revolutionised our understanding of how nutritional support can be vital in addressing AMD. The second study, AREDS2, improved the supplement formulation by:
- Removing beta-carotene, which had been linked to an increased risk of lung cancer in smokers.
- Adjusting zinc levels to safer yet equally effective amounts.
- Adding lutein and zeaxanthin, two essential macular carotenoids.
The result? A safer and more effective strategy for slowing the progression of dry AMD.


Which Nutritional Supplements Align with AREDS2 Guidelines in Australia?
Two highly regarded supplement options include:
1. Macutec Once Daily (by Stiltec – Proudly Australian Made)
Key Ingredients That Comply with AREDS2 Guidelines:
- Vitamin C – 500mg
- Vitamin E – 400 IU
- Zinc Oxide – 25mg
- Copper – 2mg
- Lutein – 10mg
- Zeaxanthin – 2mg
Recommended dosage: One tablet daily with food.
Fully adheres to the AREDS2 formula
2. Blackmores Macu-Vision Plus
- Vitamin C – 250mg
- Vitamin E – 200 IU
- Zinc Oxide – 40mg
- Copper – 1mg
- Lutein – 5mg
- Zeaxanthin – 1mg
Recommended dosage: One tablet daily with food.
Contains only half the recommended dose of lutein and zeaxanthin according to AREDS2
What Are the Drawbacks of the Original Blackmores Macu-Vision?
This product lacks both lutein and zeaxanthin and fails to meet AREDS2 guidelines in any respect. While it may provide some antioxidant support, it does not deliver the essential nutrients necessary for maintaining optimal macular health.
A Comparative Analysis: Macutec vs Macu-Vision Plus
| Ingredient | Macutec Once Daily | Macu-Vision Plus | AREDS2 Recommended Dosage |
|---|---|---|---|
| Vitamin C | 500 mg | 250 mg | 500 mg |
| Vitamin E | 400 IU (as dl-alpha tocopheryl acetate) | 200 IU | 400 IU |
| Zinc (as Zinc Oxide) | 25 mg | 40 mg | 80 mg* |
| Copper (as Cupric Oxide) | 2 mg | 1 mg | 2 mg |
| Lutein | 10 mg (FloraGLO® Lutein) | 5 mg | 10 mg |
| Zeaxanthin | 2 mg (Optisharp® Zeaxanthin) | 1 mg | 2 mg |
| Capsules per day | 1 softgel | 1 tablet | 1 dose |
| Compliance with AREDS2 Formula | Fully Match |
Partial (half dose L/Z, low C/E) |
Based on NEI AREDS2 Formula |
*AREDS2 research indicated that lower zinc doses (25 mg) were equally effective and resulted in fewer side effects compared to higher amounts of 80 mg.
Ingredient Analysis and Key Insights:
- Lutein & Zeaxanthin: Macutec Once Daily meets the AREDS2 recommendation precisely (10mg Lutein, 2mg Zeaxanthin), whereas Blackmores Macu-Vision Plus only provides half.
- Zinc: Although Macutec employs a lower 25 mg Zinc dosage, AREDS2 findings demonstrated that this amount was equally effective and associated with fewer side effects compared to higher levels.
- Vitamin E Formulation: Macutec utilises dl-alpha tocopherol; while AREDS2 utilised natural d-alpha, this form is a widely accepted substitute that does not significantly impact most users.
- Manufacturing Standards: Macutec is Australian-made under pharmaceutical GMP and incorporates premium branded lutein (FloraGLO®) and zeaxanthin (Optisharp®), both of which were used in the original AREDS2 trials.
Crucial Considerations for Selecting the Right Supplement:
Macutec is also Australian-made, featuring premium branded carotenoids that are integral to the AREDS2 study, tailored for convenient once-per-day dosing.
Macutec Once Daily offers a precise alignment with the AREDS2 formula, containing full-strength lutein (10 mg) and zeaxanthin (2 mg), while minimising excessive zinc intake.
Macu-Vision Plus, despite being marketed as an AREDS-style supplement, provides only half of the recommended L/Z dosage, lower antioxidant levels, and excess zinc that may not be necessary.
Making an Informed Decision: Which Supplement Best Meets Your Needs?
Both supplements are designed to slow the progression of dry macular degeneration; however, only one fully complies with the AREDS2 formula: Macutec Essentials. It offers:
- Full-strength, evidence-based ingredients
- Clinically proven efficacy
- Superior value and precise dosing
- Manufactured in Australia to high-quality standards
For these reasons, Eyes by Design proudly stocks Macutec Essentials, which we confidently recommend to our patients on the Central Coast and beyond.
Available in-store or for delivery throughout Australia.
Looking for Expert Guidance on Eye Health?
If you have questions about macular health, nutritional supplements, or your suitability for nutritional therapies, please do not hesitate to contact our knowledgeable team.
We provide tailored, expert advice based on the latest clinical research.
Call (02) 4369 8169
Visit us at Shop 6, Kincumber Centre, 39 Avoca Drive, Kincumber NSW 2251
Frequently Asked Questions Regarding Macutec Once Daily vs Macu-Vision Plus
What Is the AREDS2 Formula and Why Is It Critical for Eye Health?
AREDS2 represents a clinically validated combination of vitamins and minerals proven to slow the progression of dry age-related macular degeneration. This formula comprises vitamin C, vitamin E, zinc, copper, lutein, and zeaxanthin. Supplements that adhere to this formula, such as Macutec Essentials, deliver the most evidence-based protection for sustaining macular health.
What Is the Purpose of Macutec Once Daily for Eye Care?
Macutec Once Daily is specifically designed to support eye health in individuals diagnosed with dry age-related macular degeneration. It is based on the findings from the AREDS2 clinical research and aims to slow the progression of the disease by protecting the macula from oxidative damage.
Can Supplements Like Macutec or Macu-Vision Cure Macular Degeneration?
No, these supplements cannot cure the condition. However, they can significantly slow the progression of dry macular degeneration and may help in preserving vision for a longer duration. Early intervention and consistent usage are vital for achieving optimal results.
What Sets Macutec Once Daily Apart from Other Macular Supplements?
Macutec Once Daily includes all the validated AREDS2 components in a convenient once-daily capsule format. It utilises high-quality lutein and zeaxanthin identical to those utilised in the clinical trials and is manufactured in Australia, adhering to strict pharmaceutical Good Manufacturing Practice standards.
How Do Lutein and Zeaxanthin Contribute to Overall Macular Health?
Lutein and zeaxanthin are natural pigments found in the macula. They play a crucial role in forming the macular pigment, and adequate intake correlates with greater macular pigment density. This enhancement helps filter harmful blue light and protects retinal tissue from oxidative stress.
Which Supplement Is Most Suitable If I Already Have Advanced Dry Macular Degeneration?
Macutec Once Daily is the optimal choice if you seek an AREDS2-compliant supplement that contains full-strength ingredients. It is specifically designed for patients diagnosed with moderate to advanced dry AMD who aim to slow its progression.
Citation
The insights and conclusions presented in this content are derived from the findings of the Age-Related Eye Disease Study 2 (AREDS2), conducted by the National Eye Institute, part of the National Institutes of Health. This study offers a comprehensive evaluation of the effectiveness of the AREDS2 supplement formulation in decelerating the progression of age-related macular degeneration.
For additional information, please refer to the National Eye Institute’s publication regarding the AREDS2 study.
In-Depth Comparison: Macu-Vision Plus vs Macutec Once Daily for Macular Degeneration Management
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